Results Bolster Tysabri for Multiple Sclerosis
Research results disclosed at the American Academy of Neurology reveal that over two years Biogen/Elan's Tysabri was about twice as effective as existing therapries in reduceing multiple sclerosis flare-ups and was slightly better in reducing disease progression. Such results revive hope the drug, withdrawn from the market earlier this year after two, and later a third, clinical trial patient died, will return to the market.
Moyamoya disease, an extremely rare disease (one in two million in USA) causing a progressive narrowing of the internal carotid arteries carrying blood to the brain and often resulting in disabling strokes can be successfully treated by a Stanford University neurosurgeon. The disease was first characterized in Japan where moyamoya means puff of smoke and is characterized by a wispy cloud of narrowing blood vessels appearing on X-ray images. The key to successful outcomes is knowing to look for this diagnosis in patients exhibiting otherwise unexplainable symptoms; unexplainable strokes, temporary speech or vision problems, headaches, mental decline, seizures, or attacks of limb numbness and weakness. Most patients are diagnosed as children from 5 to 15, or adults from 30 to 40, and nearly two-thirds are female.
inspiring details the baseball legend's struggle with the disease that would borrow his name during the two years after he retired from the sport. These details emerge from never before published correspondence with his doctor which also shed light on experimental treatments and the medical ethics prevailing at the time. It is retching to see how doctors and spouses often hid medical realities from patients in a way that today would not be common.